Last episode
The Cobalt Fissure
s02e20 · 2026-05-04 · 01:59
What it is
In Watson a year after the death of his friend and partner Sherlock Holmes at the hands of Moriarty, Dr. John Watson resumes his medical career as the head of a clinic dedicated to treating rare disorders. Watson's old life isn't done with him, though — Moriarty and Watson are set to write their own chapter of a story that has fascinated audiences for more than a century. Watson is a medical show with a strong investigative spine, featuring a modern version of one of history's greatest detectives as he turns his attention from solving crimes to addressing the greatest mystery of all: illness, and the ways it disrupts our lives.
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Episode guide
20 this season · 33 totals02e01 A Son in the Oven 2025-10-14 02:00
A Son in the Oven
Watson and the fellows spring back into action when Mary's mother accidentally poisons herself while suffering from a rare form of dementia that is progressing with impossible speed; Sherlock Holmes resurfaces after being presumed dead.
s02e02 Back from the Dead 2025-10-21 02:00
Back from the Dead
When a microbiology university researcher returns from an expedition to Siberia, she and her team members fall ill from a possible revived pathogen; Watson catches up with his friend Sherlock Holmes after finding out he is alive.
s02e03 Expletive Deleted 2025-10-28 02:00
Expletive Deleted
Watson and the team work alongside Laila to help a patient named Maxine, a 30-year-old who looks 10.
s02e04 Happy When It Rains 2025-11-04 03:00
Happy When It Rains
Watson and the team jump into action when four people become infected with a flesh-eating bacterium; Shinwell searches for meaning as a nursing student; Adam's wedding to Lauren risks being halted.
s02e05 Lucky 2025-11-11 03:00
Lucky
While visiting another hospital, Watson becomes convinced that a man is suffering from locked-in syndrome and has been mistaken for a coma patient for over a decade; Sherlock is back in town and is staying with Watson.
s02e06 Buying Time 2025-11-18 03:00
Buying Time
Watson and the fellows race against time to save the life of Xavier, a 21-year-old athlete with a fast-growing, seemingly incurable cancer; Mycroft Holmes lets Watson know his team's work at UHOP may no longer have funding available.
s02e07 Giant Steps 2025-11-25 03:00
Giant Steps
Watson's father, Hamish, visits UHOP to introduce Watson and the fellows to his protégé, Annabelle, a saxophone prodigy with musically induced blackouts.
s02e08 Livvy Sees The Doctor 2025-12-02 03:00
Livvy Sees The Doctor
Watson and the fellows are taken hostage by a man with a bomb strapped to his chest who is desperate to find a cure for his 9-year-old daughter's illness.
s02e09 Shannon Says Bex Loves Micah 2025-12-09 03:00
Shannon Says Bex Loves Micah
Watson and the fellows help Laila's son Micah, who was injured in a car accident while pursuing his crush, Bex, with the help of his AI chatbot.
s02e10 Never Been CRISPR'd 2025-12-16 03:00
Never Been CRISPR'd
Watson's biohacker friend Hobie (aka the man with the glowing chest) returns when he rushes his new girlfriend to the Holmes Clinic after they partake in a gene-editing experiment that goes wrong. Meanwhile, Watson becomes suspicious of Sherlock.
s02e11 The Tunnel Under the Elms 2026-03-02 03:00
The Tunnel Under the Elms
Watson and the fellows race against the clock to save a man and his pregnant wife from a terrifying sinkhole. Meanwhile, Ingrid's future with her therapy group becomes unclear.
s02e12 A Family Meal 2026-03-09 02:00
A Family Meal
When a patient arrives at the Holmes Clinic plagued by a mysterious neurological disorder, Watson and the fellows discover they were forced to eat their parents amid a childhood survival incident. Meanwhile, Adam is struggling with how his future will change as a father.
s02e13 For a Limited Time Only 2026-03-16 02:00
For a Limited Time Only
Watson and the fellows fight to revive a 30-year-old woman, Audrey, after her heart inexplicably stops repeatedly until they discover she has a rare phenomenon called Lazarus syndrome. As these revivals continue, she uses the short window of time available to right her greatest wrong.
s02e14 Wrongful Life 2026-03-23 02:45
Wrongful Life
Watson is sued for Wrongful Life by a long-term patient suffering from VACTERL association, after undergoing multiple painful surgeries.
s02e15 A Third Act Surprise 2026-03-30 02:33
A Third Act Surprise
Watson and the fellows race to save the life of a young woman who needs a lifesaving kidney donation. Meanwhile, Sherlock returns to help crack unsolved cases in Pittsburgh.
s02e16 Respect the Process. Respect the Quirks 2026-04-06 02:00
Respect the Process. Respect the Quirks
Watson investigates a case involving a mentally unstable mother, with the woman's delusions serving as a mirror to his own newly discovered hallucinations.
s02e17 Unsolved Mysteries 2026-04-13 02:17
Unsolved Mysteries
After a key player disappears, the team rushes to find them before it's too late.
s02e18 Sic Semper Tyrannis 2026-04-20 02:00
Sic Semper Tyrannis
Following his brain tumor diagnosis, Watson goes on medical leave to seek treatment, leaving Mary in charge of The Holmes Clinic as a notorious South American dictator demands Watson see to his mysterious autoimmune condition personally. Meanwhile, Ingrid grows more concerned about Beck's obsession with Sasha.
s02e19 The Rule of Three 2026-04-27 02:00
The Rule of Three
As Adam's wife goes in for a C-section to deliver triplets, chaos ensues when their OB-GYN passes out in the operating room. Meanwhile, a severe storm detours Watson and Mary's trip to find a renowned doctor to remove Watson's brain tumor.
s02e20 The Cobalt Fissure 2026-05-04 01:59
The Cobalt Fissure
A seemingly random murder outside of UHOP sets the stage for the arrival of someone from Watson and Sherlock Holmes' past.